The Alphabet-backed immunotherapy developer secured nearly $588m in what was reputedly the largest ever flotation for a preclinical life sciences company.

US-based stem cell medicine developer Sana Biotechnology raised almost $588m on Wednesday in an upsized initial public offering representing an exit for GV, a subsidiary of internet and technology group Alphabet.

The company issued 23.5 million shares on the Nasdaq Global Select Market, up from a planned 15 million, priced at $25.00 each, above the $20 to $23 range set last week.

The IPO price valued Sana Bio at $4.9bn and its shares surged 40% on the first day…

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