Gilead Sciences is co-leading a $75m PIPE deal for the coronavirus drug developer, which is set take the place on Nasdaq held by FS Development Corp II later this year.

US-based oral antiviral therapy developer Pardes Biosciences agreed a reverse takeover yesterday with $75m in private investment in public equity (PIPE) financing co-led by biopharmaceutical firm Gilead Sciences.

The company is set to merge with special purpose acquisition company FS Development Corp II, which listed on the Nasdaq Capital Market in a $115m initial public offering in January this year.

Foresite Capital, the investment firm affiliated with FS Development Corp II, is co-leading the PIPE with Gilead, Frazier Life Sciences, funds and accounts advised by T Rowe Price, GMF Capital, EcoR1 Capital and Monashee Investment Management.

Founded in 2020, Pardes is developing oral antiviral drugs targeting SARS-CoV-2, the coronavirus that causes covid-19 infections. Its lead candidate, PBI-0451, is designed to prevent the virus’s main protease enzyme from working in the body.

The proceeds from the transaction will be used to improve PBI-0451 and other candidates and begin clinical trials later in the year. The startup raised $51.6m in equity funding in February this year from 36 undisclosed investors, according to a securities filing.

Pardes CEO Uri Lopatin said: “Covid-19 has been a global medical catastrophe. Over the past year, we have been focused on bringing forward PBI-0451, a viral protease inhibitor that we are developing to be a potential oral therapy for SARS-CoV-2 infections. Oral antivirals are expected to play an important role in ending this pandemic and preventing the next one.”

Edison Fu

Edison Fu is head of Asia development at Global Corporate Venturing.