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Affinia achieves $110m series B close

Affinia achieves $110m series B close

May 5, 2021 • Robert Lavine

GV, Mass General Brigham Ventures and Lonza helped Affinia Therapeutics raise $110m to commercialise work originating at Harvard.

Affinia Therapeutics, a US-based gene therapy developer based on research at Harvard Medical School, completed a $110m series B round on Monday featuring chemicals producer Lonza, internet and technology group Alphabet and healthcare provider Mass General Brigham.
EcoR1 Capital and Farallon Capital Management co-led the round, which included investment and financial services group Fidelity’s F-Prime Capital subsidiary, while Alphabet and Mass General Brigham took part through GV and Mass General Brigham Ventures respectively.
Avidity Partners, Casdin Capital, Octagon Capital, Perceptive Advisors, RA Capital Management, TCG Crossover, Woodline Partners, Atlas Venture and New Enterprise Associates (NEA) filled out the participants.
Affinia is developing gene therapies and adeno-associated virus (AAV) vectors to treat disorders affecting the muscles and central nervous system. It is allocating the series B proceeds to platform development and advancing its drug pipeline toward clinical trials.
The company’s technology is based on research by Luk Vandenberghe, an associate professor at Harvard University’s Massachusetts Eye and Ear teaching hospital and Harvard Medical School.
F-Prime and NEA co-led a $60m series A round for the startup in March 2020 that included Lonza healthcare provider Partners Healthcare’s Partners Innovation Fund, Atlas Venture and Alexandria Venture Investments, which invested on behalf of real estate investment trust Alexandria Real Estate Equities.
Rick Modi, Affinia’s CEO, said: “Since founding the company, we have had the interest of leading biotech investors as well as strategic partners who see the potential of our gene therapy discovery platform to engineer novel vectors that overcome the limitations of conventional serotypes.
“We are excited to partner with this syndicate of top investors to expand our platform to regulatory elements and work toward the next generation of one-time, potentially curative medicines for broader use.”
– A version of this article first appeared on our sister site, Global Corporate Venturing.
 

GV, Mass General Brigham Ventures and existing investor Lonza helped Affinia Therapeutics raise $110m that will fund the progress of its gene therapy candidates.

US-based gene therapy developer Affinia Therapeutics completed a $110m series B round on Monday featuring chemicals producer Lonza, internet and technology group Alphabet and healthcare provider Mass General Brigham.

EcoR1 Capital and Farallon Capital Management co-led the round, which included investment and financial services group Fidelity’s F-Prime Capital subsidiary, while Alphabet and Mass General Brigham took part through GV and Mass General Brigham Ventures respectively.

Avidity Partners, Casdin Capital, Octagon Capital, Perceptive Advisors, RA Capital Management, TCG Crossover, Woodline Partners, Atlas Venture and New Enterprise Associates (NEA) filled out the participants.

Affinia is developing gene therapies and adeno-associated virus (AAV) vectors to treat disorders affecting the muscles and central nervous system. It is allocating the series B proceeds to platform development and advancing its drug pipeline toward clinical trials.

The company’s technology is based on research by Luk Vandenberghe, an associate professor at Harvard University’s Massachusetts Eye and Ear teaching hospital and Harvard Medical School.

F-Prime and NEA co-led a $60m series A round for the startup in March 2020 that included Lonza healthcare provider Partners Healthcare’s Partners Innovation Fund, Atlas Venture and Alexandria Venture Investments, which invested on behalf of real estate investment trust Alexandria Real Estate Equities.

Rick Modi, Affinia’s CEO, said: “Since founding the company, we have had the interest of leading biotech investors as well as strategic partners who see the potential of our gene therapy discovery platform to engineer novel vectors that overcome the limitations of conventional serotypes.

“We are excited to partner with this syndicate of top investors to expand our platform to regulatory elements and work toward the next generation of one-time, potentially curative medicines for broader use.”

Robert Lavine

Robert Lavine is special features editor for Global Venturing.

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