Eli Lilly-backed inflammatory disease drug developer has filed to raise up to $100m in an initial public offering in the United States.

Carisma Therapeutics has increased its series B round to $59m thanks to an extension backed by IP Group, Penn Medicine and 4Bio Capital.

Penn Medicine contributed to a $12m extension for the cancer immunotherapy developer's series B round, which already inlcuded Livzon, Merck & Co and AbbVie.

RTW Investments has a series C for the UT Southwestern and Gladstone Institutes spinout, which will progress its lead asset into the clinic.

Sutter Health, Novo, Sentara and Health Care Service Corporation are set to exit the virtual healthcare provider in an acquisition of undisclosed size.

Axel Springer has exited the advertising data technology provider, which has been bought by Rokk3r together with its Matrix Labs spinoff for $19.5m.

Siemens' Next47 unit led a series B round for the email security platform developer, increasing its total funding to more than $46m.

Judith Cone, the university’s vice-chancellor for innovation, entrepreneurship and economic development, has announced her intention to retire next month.

Jonathan Barada has joined IU Ventures as vice-president and his focus will include the firm’s Philanthropic Venture Fund.

AstraZeneca likely received over $1bn from selling its shares, having invested $140m in the publicly listed covid-19 vaccine developer in 2015.