Toronto’s AmacaThera is preparing clinical trials of a drug delivery hydrogel that could diminish the need for prescription opioid painkillers after surgery.

Nanomaterials provider Nanogap, a spinout of University of Santiago de Compostela, received $2.1m from Repsol's Corporate Venture vehicle.

University of Bristol Enterprise Fund has returned with more cash for irrigation system developer Lettus Grow, founded by Bristol graduates and students.

Indiana University Philanthropic Venture Fund has joined Purdue Ventures and university-backed VC vehicle Indiana Seed Fund as an investor in healthcare communication platform Diagnotes.

PetaGene hopes its data compression technology will aid the genomic sequencing industry.

NUI Galway-linked businesses to have secured backing last year include kidney reflux test spinout Kite Medical and medical implant developer Loci Orthopaedics.

Spun out of Tübingen, Justus Liebig University Gießen and Münster, Atriva Therapeutics has raised an initial $1.4m to progress next-generation antiviral drugs for conditions including influenza.

Based on research from the universities of Bristol and Nottingham, Exonate has now raised $9m to develop a topical eye drop for conditions including diabetic macular edema.

The funding for Shimane's Nanotechnology Project Center came from San-in Godo Bank through an industry-academia cooperation program.

HTGF, Think.Health Ventures and Business Angels have also supplied funding to Max Planck Institute for Biochemistry mass spectrometry spinout PreOmics.