Amazon Alexa Fund and Specialized Bicycle Components vehicle Zone 5 Ventures helped the social exercise platform raise money at a valuation above $1bn.

The autoreactive and neuro-inflammatory disease therapy developer closed a $77.5m round co-led by Sanofi Ventures that took its total funding to more than $117m.

The precision medicine developer attracted returning investors Novo, Novartis Venture Fund and Johnson & Johnson Innovation – JJDC for a crossover financing round.

Escape Bio, a spinout of Gladstone Institutes, has secured the return of Osage University Partners, Novartis, Novo and Johnson & Johnson.

The investment firm supplied $50m for telehealth platform developer MDLive, which already counts Sentara, Cigna, Sutter Health, Novo and HCSC as investors.

The Johns Hopkins spinout has raised cash from OUP as it looks to move its first candidate, targeting skin itch complications, into the clinic.

The notification software startup received backing from strategic investors Twilio, Slack and SendGrid in a $10.1m round that will fund hiring and product development.

Mission Bay Capital has placed a bet on Symbiome, creators of a skin care range intended to emulate our ancestor’s microbiome.

Baxter International scored an exit as dialysis machine developer Outset Medical floated above its range in an upsized offering.

Astellas and Celgene-backed immuno-oncology therapy developer Oncorus has filed to raise up to $86.3m following more than $150m in funding.