The gains came against a backdrop of falling net profits and cash reserves that will test Karolinska Development as it looks ahead to convertible debt obligations.

Spun out of Inesc Tec under a strategic agreement with Frontier IP, Insignals hopes to commercialise a surgical guidance device for brain implants to treat conditions including Parkinson's.

Indiana University has retooled its entrepreneurial support offering to enhance its services in business case development, executive recruitment and the sourcing of capital.

Venture capital firm Frazier Healthcare Partners has spun out a US-based antibiotics developer with the help of grant funding from a Boston University-operated body and a $8.5m series A round.

Cytonus Therapeutics has spun out of UC San Diego to develop cell-based containers for the effective release of therapeutics including cancer drugs.

MIT has launched an as-yet unnamed spinout to develop a smart drug-delivery pill to help plan more effective treatment regimens for patients.

US-based Blue Water Vaccines has an option on University of Oxford research into a universal influenza shot and is looking to raise $15m in funding.

Evervault is pursuing seed funding for encryption software that protects compromised networks, while MyStudyPal has launched an academic timetabling app.

Oxford University Innovation reported a record $698m of funding for its portfolio businesses in a year which brought its total number of spinouts to more than 170.

Dietary suggestion software spinout Food Genes and Me compiles personalised healthy eating tips based on uploaded DNA reports from external genetic analysis tools.