Novo Ventures leads a $20m B round into US-based osteoarthritis company Flexion Therapeutics.

The $8m extension brings Rhythm's B round to $33m and the total raised to $73m in less than two years.

Reed Elsevier Ventures leads a $10m Series B for US-based network analytics mapper Activate Networks, investing alongside healthcare alliance Premier and Excel Venture Management.

A division of Hitachi Capital America Corp, Hennessey Capital, has led a $23m Series B round into US-based eco bus company Proterra.

RTP was part of consortia investing $5.25m in MabVax Therapeutics and $6.2m in Datadog.

US Pharmaceutical corporation Eli Lilly and financial services provider Fidelity Investments, invested $25m in the expanding Chinese bioscience manufacturer Innovent Biologics.

SR One leads the $37.5m B round for the gene therapy company with existing corporate investor MedImmune Ventures also investing.