Pfizer's corporate venturing unit invested in the pharmaceutical company along with New Enterprise Associates, Fidelity Biosciences, ProQuest Investments, Harris and Harris Group, and Rho Ventures.

Chris Coburn, executive director of Cleveland Clinic Innovations, said: "There really can be no more significant alliance than this teaming of our two institutions up and down I-71. We will help to change the face of innovation in the state."

Invesco Perpetual, the fund manager, and Imperial Innovations, the London Stock Exchange-listed spin-off from Imperial College London, are joined by The Cancer Prevention and Research Institute of Texas and the Wellcome Trust supporting Cell Medica's growth.

PTC, which is backed by Celgene and Credit Suisse and various venture firms,

Rusnano MedInvest, part of Rusnano, helps the US-based biopharmaceutical company, previously invested in by Nestle-backed BioPacific Ventures, raise a series B extension.

BioMed Ventures, the corporate venturing unit of the eponymous biotech real estate company, and BASF-backed Fintech Gimv were joined in the round backing the regenerative medical company by venture firms including Sofinnova Ventures, Split Rock Partners and BioMed Ventures.

The Korea-listed company that makes men's clothes, backs the US-based pharmaceutical company.

Boston Scientific is joined by venture firms including Glengary Ventures, RiverWest Venture Partners and Physician Investment Group.

Alongside Kaiser Permanente in the C round are venture capital firms Aisling Capital, which led the round, Care Capital, Investor Growth Capital, ProQuest Investments and Novitas Capital.