Bellerophon, which was spun out of biopharmaceutical company Ikaria last year, has filed for an initial public offering on Nasdaq.

Hanmi Pharmaceutical has licensed an eye disease treatment from Allegro Ophthalmics, and will make a concurrent $20m investment.

CoLucid Pharmaceuticals, which is working on a treatment for migraines, has secured backing from investors including Novo to take its total financing above the $100m mark.

The medication tracking software provider raised the money in a Kaiser Permanente-led series B round that also included Rex Healthcare.

Fosun Pharma will invest $35m in the generic pharmaceuticals producer, which will invest the cash in developing its product pipeline.

Commercialisation firm PureTech raises an additional $50m to bring its October 2014 fundraising up to $107m.

Parkwalk Advisors back Cambridge spin-out Fluid Analytics in series A round.

The two companies have set up a joint investment company which will invest a total of up to $100m in digital medicine startups.