Johnson & Johnson and AbbVie bought a combined $55m of stock as the biopharmaceutical company, already listed in Europe, went public on Nasdaq.

US-based biotech startup Denali launches with $217m in backing from Arch Venture Partners and others.

North West Fund returns for second six-figure investment into Liverpool canine-focused 3D printer spin-out Fusion Implants.

Qura Therapeutics will develop HIV treatments in partnership with University of North Carolina at Chapel Hill, a venture in which it is investing $20m.

Fred Hutchinson spin-out Adaptive Biotechnologies raises $195m for immunotherapy treatments.

Healthcare partnership Intel-GE launches collaboration with Mississippi University on Innovation living Lab.

Bank of Ireland Seed and Early Stage Fund plans to divest 25% of its portfolio in the next year, beginning with medical device developer NeoSurgical.

Novo, GlaxoSmithKline and Merck-backed molecular profiling platform HTG offered almost 3.6 million shares priced at $14 each.

Pet medicine developer Jaguar Animal Health, backed by Napo Pharmaceuticals, raised $20m after receiving $2.2m of venture funding.