Legend Holdings reinvested in life sciences R&D services provider Pharmaron, co-leading a $280m round closed four years after a $40m series C.

Accolade has secured an additional $16m for a McKesson and Independence Health-backed round, boosting it to $38.6m and its overall funding to more than $90m.

The Illumina-backed startup has launched with $44m and will develop therapeutics based on how the gut communicates with the brain and other organs.

Allena, which is developing treatments for kidney diseases, took its overall funding to $93m in a round featuring returning investor Pharmstandard.

Express Scripts has inked a deal with Lewis & Clark Ventures to invest $25m in software developers, device makers and life sciences startups at series A and B stage.

Health analytics provider GNS has attracted Celgene, Cambia Health, Mitsui and Heritage Provider Network to its series C round, increasing its total funding to nearly $35m.

The Alphabet-backed healthcare provider plans to spend the funding on national expansion, and the strengthening of its enterprise, mobile and digital offerings.