The eye disease treatment developer has raised $48m in funding from investors including Santen Pharmaceutical, which is also a research partner.

Pi-Cardia will use the funding to complete development of the next generation of its aortic valve stenosis treatment technology.

The paediatric care startup raised the cash in a series B round featuring real estate developer Longfor Properties.

The round, backed by AmorePacific's corporate venturing unit, will support the clinical advancement of Elastagen's cosmetic surgery technology.

The startup, which is developing treatments for Alzheimer's disease, received the money in a Pfizer-led round that also included Takeda's corporate venturing unit.

Monsanto Growth Ventures, which invests from seed-stage onwards, has backed 11 companies operating in the US, Spain and Estonia.

Amgen and AbbVie have joined existing backers including Merck and Alphabet for a round led by the corporate and UK government-backed Dementia Discovery Fund.

The GE and Elbit Imaging-backed company uses focused ultrasound to treat various disorders, and has now raised more than $155m since 1999.

Cancer screening test developer Grail has been spun out of biotech company Illumina with a $100m series A round co-led by Illumina and Arch Venture Partners.