Spun out of Boston University by Allied Minds in December last year, Signature Medical has secured $2.5m in series A funding from investors including Bose.

Rodeo Therapeutics has developed therapies to regenerate tissue, based on research undertaken at Case Western Reserve University and University of Texas Southwestern Medical Center.

Pfizer Venture Investments led the small-molecule cancer drug developer's $38.6m series C round, which included Novartis, GlaxoSmithkline, AbbVie and Astellas.

Living Pharma, an immunotherapy developer, has been acquired just 18 months after being spun out from University of Maryland.

Blue Cross Blue Shield of Massachusetts' Zaffre Investments fund has joined the investors in electronic health record analytics platform Arcadia Healthcare Solutions.

BGU spinout Neuroderm, which is developing clinical-stage pumps containing medicine for Parkinson’s, has been bought by Mitsubishi Tanabe Pharma for $1.1bn.

Vitreoretinal disease therapy developer Allegro Ophthalmics has raised $10.7m in funding, 18 months after receiving $20m from Hanmi Pharmaceutical.