The investment, backed by Itochu, follows a $33.7m series E round featuring Qualcomm Life Fund and Hearst Health Ventures in 2016.

Tencent has led a series C round for the health e-commerce company, which will use the cash to bolster its business and technology development efforts.

Pfizer and Johnson & Johnson were among the returning backers to support a $100m series C round for Reflexion Medical, which secured the Rise Fund as lead investor.

Duke spinout Element could generate as much as $30m from the sale, which will enable UCB to boost its research capabilities.

Accolade has raised $50m from a consortium of investors that included McKesson Ventures, which previously injected $22.5m in 2015.

Newcastle and Durham universities have been joined by regional peers Northumbria and Sunderland in a commercialisation drive backed by government funding.

The Crossover I vehicle has been backed by CNP Assurances and an unnamed Chinese biopharmaceutical firm, and will target both late-stage private and public companies.

Aptus Therapeutics-backed Alzheon has set its pricing range at $13 to $15 and could raise almost $86.3m if underwriters take up their option to purchase additional shares.