Novo-backed Cirius Therapeutics, which was supported at launch by Metabolic Solutions Development Company, will put the IPO proceeds into its lead liver disease treatment.

Slack, which is backed by Comcast Ventures, SoftBank and GV, and valued at $7.1bn, is set to forego an initial public offering and instead opt for a direct listing.

MRL Ventures, GV, AbbVie Ventures, Lilly Asia Ventures and Amgen Ventures are all in line to exit the immuno-neurology drug developer.

Cali Group owns a 17.6% in the online gaming platform and eSports tournament operator, whose other investors include Viacom, Axiomatic, DMG and Cinemark.

Tencent owns a 38% stake in the online brokerage, which has filed to go public in the US with a smaller target than previously reported.

The immuno-oncology drug developer has filed for an $86.5m offering, having raised more than $115m in equity funding from investors including Taiho and Eli Lilly.

The Rakuten-backed social media and e-commerce company, valued at more than $12bn, will select underwriters next month and could go public as soon as April.

Tencent reportedly owns more than 30% of online brokerage Futu Securities, which has confidentially filed to go public, targeting a $2.5bn valuation.

Investors including co-founder and Harvard professor Timothy Springer scored exits as mRNA therapy developer Moderna floated in the largest biotech IPO of all time.