Pfizer is the largest shareholder of Alzheimer's drug developer Cortexyme, which has filed to raise up to $86.3m in its initial public offering.

Africa-focused e-commerce company Jumia floated in the middle of its range, with more than half the shares being bought by existing corporate investors.

SoftBank Vision Fund and Alphabet are among the largest shareholders in Uber, which has filed for an offering that could value it at $100bn, a decade after it was founded.

The corporate-backed ride hailing service intends to seek a valuation of up to $100bn in its initial public offering and plans to officially file tomorrow.

The cosmetic surgery booking and reviews platform, which counts Tencent among its investors, has filed to go public in the US.

Lundbeckfonden Ventures-backed Trevi has filed for an $86.2m IPO to fund clinical trials for pruritus-focused drug treatments.

The Shea Ventures-backed social fashion marketplace has hired underwriters for an initial public offering that would follow almost $150m in funding.

The biopharmaceutical developer floated at the top of its range and will secure $65.9m from existing backer Merck & Co through a private placement.

Alibaba-backed social influencer network Ruhnn floated in the middle of its range in the US, with Weibo buying $8m of shares.

The Oxford University genetic sequencing spinout is reportedly mulling an IPO that would provide exits to investors including commercialisation firm IP Group.