The China-based e-commerce company established its place at the internet's head table with an IPO set to close at $25bn, showing the value of strategic investment.

The Pharmstandard-backed pharmaceutical company is seeking to raise the cash in an IPO four months after it closed part of a $45m series D round.

The Novartis-backed pharmaceutical company will use the proceeds to fund pivotal tests for its prostate cancer drug.

Healthcare management technology company TriZetto has been acquired by IT and consulting company Cognizant Technology Solutions for $2.7bn.

Kolltan, which is backed by Purdue Pharma and Gilead Sciences, will use the proceeds to advance its candidates through early-stage clinical trials.

The internet company has now made about $300m in total from share sales in publicly traded payment company Qiwi.

Covagen is a spin-out of ETH Zurich.

The medical device developers have agreed a merger, and Merck and Mayo Clinic, both of which have funded Preventice, will continue to support the new company.

The car rental company is one of several cornerstone investors that will invest $30m as the China-based company seeks $467m from a Hong Kong initial public offering.