Thrive Earlier Detection, the developer of an early cancer screening blood test invented at JHU, has raised $257m in series B funding.

Sema4, spun out of Icahn School of Medicine, has achieved a valuation of more than $1bn following a $121m series C round.

Mount Sinai Health System spinoff Sema4 has achieved a valuation of more than $1bn following a $121m series C round that featured all existing external shareholders.

Line’s on-demand delivery service has attracted $110m from BRV Capital as it merged with restaurant listings website Wongnai Media.

Heal has entered into a strategic partnership with Humana that includes a $100m investment from the corporate and will support an expansion into additional US cities.

Mitsui and Virgin-backed remittance service TransferWise has bolstered its valuation to $5bn, up from $3.5bn, through a $319m secondary share sale.

Co-founded by faculty from Columbia University and University of Melbourne, Praxis Precision Medicines targets CNS disorders.

GPI Capital and JPMorgan Chase have injected $150m into Pharmapacks, whose backers already include Reckitt Benckiser, McKesson, Sealed Air and Emerson Group.

Novo Holdings returned for a $110m series C1 round for Praxis Precision Medicines, four months after the gene therapy developer emerged from stealth with $100m in funding.

JD.com and Expedia-backed online travel agency Traveloka has picked up $250m in funding led by an undisclosed investor that could be Qatar Investment Authority.